Rituximab: a useful drug for a repeatedly relapsed hairy cell leukemia patient

Ann Hematol. 2002 Dec;81(12):736-8. doi: 10.1007/s00277-002-0559-z. Epub 2002 Nov 9.

Abstract

We describe a case of complete response in a patient with hairy cell leukemia, relapsed after treatment with interferon-alpha, 2'-deoxycoformicin, and 2-chlorodeoxyadenosine, and then successfully treated with rituximab. A fourfold reduction of leukemic cells was observed concomitantly with restoration of normal blood count and differential.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antibodies, Monoclonal / administration & dosage*
  • Antibodies, Monoclonal, Murine-Derived
  • Cladribine / administration & dosage
  • Humans
  • Interferon-alpha / administration & dosage
  • Leukemia, Hairy Cell / drug therapy*
  • Male
  • Pentostatin / administration & dosage
  • Recurrence
  • Remission Induction
  • Rituximab
  • Salvage Therapy

Substances

  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Murine-Derived
  • Interferon-alpha
  • Pentostatin
  • Cladribine
  • Rituximab