Abstract
Diabetes mellitus is one of the major causes of chronic renal failure. Typical findings of diabetic nephropathy are early hyperfiltration followed by microalbuminuria and overt proteinuria, resulting in a progressive decrease in glomerular filtration rate. Rapidly progressive glomerulonephritis has rarely been reported in patients with diabetes mellitus. Here, we describe a patient with MPO-ANCA-associated vasculitis, presenting with pulmonary-renal syndrome. Immunosuppressive treatment, including pulse methyl-prednisolone and cyclophosphamide, was administered and the disease was resolved.
MeSH terms
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Antibodies, Antineutrophil Cytoplasmic / analysis
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Antibodies, Antineutrophil Cytoplasmic / immunology*
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Cyclophosphamide / analysis
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Diabetes Mellitus, Type 2 / complications*
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Drug Therapy, Combination
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Follow-Up Studies
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Glomerulonephritis / complications
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Glomerulonephritis / drug therapy
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Glomerulonephritis / immunology*
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Humans
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Immunosuppressive Agents / administration & dosage
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Lung Diseases / complications
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Lung Diseases / drug therapy
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Lung Diseases / immunology*
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Male
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Methylprednisolone / administration & dosage
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Middle Aged
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Peroxidase / analysis
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Peroxidase / immunology*
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Risk Assessment
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Severity of Illness Index
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Syndrome
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Treatment Outcome
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Vasculitis / complications
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Vasculitis / drug therapy
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Vasculitis / immunology*
Substances
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Antibodies, Antineutrophil Cytoplasmic
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Immunosuppressive Agents
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Cyclophosphamide
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Peroxidase
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Methylprednisolone