Hallucinations and sleep-wake cycle in PD: a 24-hour continuous polysomnographic study

Neurology. 2002 Dec 24;59(12):1979-81. doi: 10.1212/01.wnl.0000038351.32678.4a.

Abstract

Twenty-four-hour ambulatory polysomnography was performed in 20 patients with PD who were having visual hallucinations (12 men and 8 women, mean age 70 +/- 6 years). Visual hallucinations were clearly related to daytime NREM sleep or nocturnal REM sleep in 33% of the instances. The data reinforce the hypothesis that neural mechanisms implicated in generating sleep and, in particular, in dream imagery play a role in the occurrence of visual hallucinations in PD.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Electroencephalography
  • Female
  • Hallucinations / etiology*
  • Humans
  • Male
  • Monitoring, Ambulatory
  • Parkinson Disease / complications
  • Parkinson Disease / psychology*
  • Polysomnography*
  • Sleep / physiology*
  • Sleep, REM / physiology
  • Wakefulness / physiology*