We have developed a relational database, called the General Repository for Interaction Datasets (The GRID; http://biodata.mshri.on.ca/grid) to archive and display physical, genetic and functional interactions. The GRID displays data-rich interaction tables for any protein of interest, combines literature-derived and high throughput interaction datasets, and is readily accessible via the World Wide Web. Interactions parsed in the GRID can be viewed in graphical form with a versatile visualization tool called Osprey.