[Intrathecal morphine for postoperative analgesia in cardiac surgery]

Medicina (Kaunas). 2002:38 Suppl 2:221-3.
[Article in Lithuanian]

Abstract

Objective: The aim of study was to evaluate features for spinal morphine in undergoing coronary artery bypass surgery in early postoperative time and side effects of opioids.

Material and methods: Two groups of patients undergoing coronary artery bypass surgery were analyzed. In first group (15 patients) spinal morphine 2 mg and general anesthesia was used, control group (22 patients) - just general anesthesia. Postoperative pain was analyzed with VAS (Visual Analogical Scale). For analgesia, after surgery, was used piritramide via i/v in both groups. Dose of piritramide, extubation time and side effects was analysed after surgery.

Results: In first group dose of piritramide was 4.5+/-1.1 mg, in control group - 16.5+/-1.1 mg (p<0.05). Extubation time in both groups (354+/-36 min. and 279+/-17 min.) and side effects (nausea and vomiting) was similar.

Conclusion: Spinal morphine decreased pain after cardiosurgery and don't increased extubation time and side effects of opioids.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Aged
  • Analgesics, Opioid / administration & dosage*
  • Analgesics, Opioid / therapeutic use
  • Anesthesia, General
  • Coronary Artery Bypass*
  • Data Interpretation, Statistical
  • Female
  • Humans
  • Injections, Spinal
  • Male
  • Middle Aged
  • Morphine / administration & dosage*
  • Morphine / therapeutic use
  • Pain Measurement
  • Pain, Postoperative / diagnosis
  • Pain, Postoperative / prevention & control*
  • Pirinitramide / administration & dosage*
  • Pirinitramide / therapeutic use
  • Postoperative Care

Substances

  • Analgesics, Opioid
  • Pirinitramide
  • Morphine