[Expression of genes coding NGF and BDNF human proteins in embryos of transgenic stocks of Drosophila melanogaster]

G V Pavlova; A A Efanov; V N Bashkirov; E A Modestova; I B Mertsalov; L I Korochkin

[Expression of genes coding NGF and BDNF human proteins in embryos of transgenic stocks of Drosophila melanogaster]

Tsitologiia. 2002;44(11):1104-8.

[Article in Russian]

Authors

G V Pavlova¹, A A Efanov, V N Bashkirov, E A Modestova, I B Mertsalov, L I Korochkin

Affiliation

¹ Institute of Gene Biology RAS, Moscow.

PMID: 12561731

Abstract

Transgenic Drosophila stocks were selected. These stocks contained human ngf and bdnf genes under Drosophila heat-shock promoter. The expression of foreign genes during Drosophila development was demonstrated with Northern and whole mount hybridization.

Publication types

English Abstract

MeSH terms

Animals
Animals, Genetically Modified
Brain-Derived Neurotrophic Factor / biosynthesis
Brain-Derived Neurotrophic Factor / genetics*
Drosophila melanogaster / embryology*
Drosophila melanogaster / genetics
Drosophila melanogaster / metabolism
Embryo, Nonmammalian
Gene Expression Regulation, Developmental*
Heat-Shock Proteins / genetics
Humans
Molecular Probe Techniques
Nerve Growth Factors / biosynthesis
Nerve Growth Factors / genetics*
Promoter Regions, Genetic
Transgenes

Substances

Brain-Derived Neurotrophic Factor
Heat-Shock Proteins
Nerve Growth Factors