Objective: To investigate the effect of cordyceps sinensis (CS) on the Th1/Th 2 cytokines and recurrence in patients with Condyloma Acuminatum (CA).
Method: Double-antibody sandwich ELISA was used to study the serum level of IL-2 and IL-10 in 34 patients treated with CS(CS group) and 29 patients in control group. The recurrence rate of CA was observed.
Result: After treated with CS, the serum levels of IL-2 and IL-10 significantly increased and decreased respectively (P < 0.05 or 0.01). No significant change occurred in control group. The recurrence times of CA in patients of CS group after electrocauterization were significantly lower than control group (P < 0.05).
Conclusion: CS might recover the balance of Th1/Th2 cytokines and enhance Th 1 immune response in patients with CA, and reduced the recurrence of CA.