Pulmonary eosinophilia following lung transplantation for sarcoidosis in two patients

Susan G Gerhardt; Rubin M Tuder; Reda E Girgis; Stephen C Yang; John V Conte; Jonathan B Orens

doi:10.1378/chest.123.2.629

Pulmonary eosinophilia following lung transplantation for sarcoidosis in two patients

Chest. 2003 Feb;123(2):629-32. doi: 10.1378/chest.123.2.629.

Authors

Susan G Gerhardt¹, Rubin M Tuder, Reda E Girgis, Stephen C Yang, John V Conte, Jonathan B Orens

Affiliation

¹ Department of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins Hospital, Baltimore, MD, USA.

PMID: 12576393
DOI: 10.1378/chest.123.2.629

Abstract

Pulmonary eosinophilia is an uncommon problem in lung transplant recipients. We report the unique occurrence of two cases of pulmonary eosinophilia in pulmonary allografts for sarcoidosis. Both patients rapidly acquired bronchiolitis obliterans syndrome (BOS) after resolution of pulmonary eosinophilia. It is known that peripheral eosinophilia is a marker for pulmonary allograft rejection, but its potential in the pathogenesis of BOS is unclear.

Publication types

Case Reports

MeSH terms

Biopsy
Bronchiolitis Obliterans / diagnosis
Bronchiolitis Obliterans / pathology
Female
Graft Rejection / diagnosis
Graft Rejection / pathology
Humans
Lung / pathology
Lung Transplantation* / pathology
Middle Aged
Postoperative Complications / diagnosis
Postoperative Complications / etiology*
Postoperative Complications / pathology
Pulmonary Eosinophilia / diagnosis
Pulmonary Eosinophilia / etiology
Pulmonary Eosinophilia / pathology
Sarcoidosis, Pulmonary / pathology
Sarcoidosis, Pulmonary / surgery*
Transplantation, Homologous