Injectable calcium phosphate bone cement Norian SRS for the treatment of intra-articular compression fractures of the distal radius in osteoporotic women

Arch Orthop Trauma Surg. 2003 Feb;123(1):22-7. doi: 10.1007/s00402-002-0458-8. Epub 2003 Jan 11.

Abstract

Background: Distal radius fracture often presents a metaphyseal void which is more extended in elderly, osteoporotic patients. Bone graft and bone substitutes are reported to be beneficial in maintaining metaphyseal reduction.

Methods: We performed a prospective study on 52 menopausal, osteoporotic women with unstable intra-articular distal radius fractures to compare the outcome of percutaneous pinning and immobilisation in a cast for 6 weeks with that using injectable calcium phosphate bone cement (Norian Skeletal Repair System, SRS) to supplement pin and screw fixation and immobilisation in a cast for 3 weeks. All patients were reviewed 2 years (range 21-29 months) after surgery.

Results: Patients treated with SRS had better functional outcome, restoration of movement and grip strength ( p<0.001). In this group there was 1 mm loss of radial length, 3 degrees loss of radial inclination and 7 degrees loss of palmar tilt. In the control group radial length decreased 3 mm, radial inclination decreased 11 degrees and palmar tilt 12 degrees. Loss of reduction was significantly higher in the control group ( p<0.001).

Conclusion: We conclude that the use of Norian SRS to supplement pin and screw fixation is effective in maintaining the reduction of unstable intra-articular distal radius fractures in osteoporotic patients and provides a better clinical outcome than percutaneous pinning.

MeSH terms

  • Aged
  • Bone Cements
  • Calcium Phosphates / therapeutic use*
  • Female
  • Fracture Fixation, Internal / instrumentation
  • Fracture Fixation, Internal / methods*
  • Fracture Healing / physiology
  • Hand Strength
  • Humans
  • Injections, Intralesional
  • Injury Severity Score
  • Middle Aged
  • Osteoporosis, Postmenopausal
  • Probability
  • Prospective Studies
  • Radius Fractures / diagnostic imaging
  • Radius Fractures / surgery*
  • Range of Motion, Articular
  • Recovery of Function
  • Risk Assessment
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Wrist Injuries / diagnostic imaging
  • Wrist Injuries / surgery*

Substances

  • Bone Cements
  • Calcium Phosphates
  • alpha-tricalcium phosphate
  • tetracalcium phosphate
  • calcium phosphate, monobasic, anhydrous
  • calcium phosphate
  • calcium phosphate, dibasic, anhydrous