Rationale and study design for a multicenter, randomized, double-blind, placebo-controlled study of the effects of tolvaptan on the acute and chronic outcomes of patients hospitalized with worsening congestive heart failure

Am Heart J. 2003 Feb;145(2 Suppl):S51-4. doi: 10.1067/mhj.2003.154.
No abstract available

Publication types

  • Clinical Trial
  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Antidiuretic Hormone Receptor Antagonists*
  • Arginine Vasopressin / blood
  • Arginine Vasopressin / physiology*
  • Benzazepines / therapeutic use
  • Disease Progression
  • Double-Blind Method
  • Heart Failure / blood
  • Heart Failure / drug therapy*
  • Hospitalization
  • Humans
  • Patient Selection*
  • Prospective Studies
  • Receptors, Vasopressin / physiology
  • Research Design
  • Tolvaptan

Substances

  • Antidiuretic Hormone Receptor Antagonists
  • Benzazepines
  • Receptors, Vasopressin
  • Arginine Vasopressin
  • Tolvaptan