[Preimplantation genetic diagnosis: two successful cases]

Fan Jin; Chen-Ming Xu; Hui-Juan Gao; Yi-Min Zhu; Yu-Li Qian; Ying-Hui Ye; Fu-Zhen Zhou; He-Feng Huang

doi:10.3785/j.issn.1008-9292.2002.03.003

[Preimplantation genetic diagnosis: two successful cases]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2002 Jun;31(3):149-150. doi: 10.3785/j.issn.1008-9292.2002.03.003.

[Article in Chinese]

Authors

Fan Jin¹, Chen-Ming Xu, Hui-Juan Gao, Yi-Min Zhu, Yu-Li Qian, Ying-Hui Ye, Fu-Zhen Zhou, He-Feng Huang

Affiliation

¹ The Affiliated Obstetrics and Gynecology Hospital, College of Medical Sciences, Zhejiang University, Hangzhou 310006, China.

PMID: 12596300
DOI: 10.3785/j.issn.1008-9292.2002.03.003

Abstract

OBJECTIVE: To establish a technology of preimplantation genetic diagnosis. METHODS: Intracytoplasm sperm injection and blastomere biopsy were performed on two women at the advanced age with the fallopian tube obstruction. Normal embryos were selected for embryo transfer after fluorescence in-situ hybridziation in biopsied blastomere. RESULTS: The levels of serum HCG were increased 20 days after embryo transfer and ultrasonography in 16 gestation weeks showed the fetal growth and structure are normal. CONCLUSION: Two successful clinical pregnancies achieved after preimplantation genetic diagnosis.