[Comparative study on pharmacodynamic effects of yinqiao powder decoction and its granule]

Zhong Yao Cai. 2002 Feb;25(2):114-7.
[Article in Chinese]

Abstract

Objective: To compare the pharmacodynamic effects of Yinqiao Powder on dividual decoction, admixture decoction and granule.

Methods: The mouse and rat inflammatory models were established by dimethylbenzene and carrageenin respectively. The rabbit model was established by typhoid Vi polysaccharide bacterin through ear vein and serolysin was induced by chick red cell. The effects of different dosage forms on inflammation antipyresis and inhibiting serolysin were observed.

Results: All three dosage forms of Yinqiao Powder could inhibit mouse auricle swelling and rat toe swelling, possessed the antithemic action and could accelerate the formation of serolysin(p < 0.01). But there were no difference among these three dosage forms in pharmacodynamic effects.

Conclusions: Three dosage forms of Yinqiao Powder had the similar effects in above-mentioned pharmacodynamic markers.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Analgesics, Non-Narcotic / administration & dosage
  • Analgesics, Non-Narcotic / isolation & purification
  • Analgesics, Non-Narcotic / pharmacology
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
  • Anti-Inflammatory Agents, Non-Steroidal / isolation & purification
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Drug Combinations
  • Drugs, Chinese Herbal / administration & dosage
  • Drugs, Chinese Herbal / pharmacology*
  • Edema / chemically induced
  • Edema / pathology*
  • Female
  • Forsythia / chemistry
  • Lonicera / chemistry
  • Male
  • Mice
  • Plants, Medicinal* / chemistry
  • Rabbits
  • Rats

Substances

  • Analgesics, Non-Narcotic
  • Anti-Inflammatory Agents, Non-Steroidal
  • Drug Combinations
  • Drugs, Chinese Herbal