Hypoglossal neurinoma presenting with intratumoral hemorrhage

J Clin Neurosci. 2002 Nov;9(6):716-9. doi: 10.1054/jocn.2001.1109.

Abstract

Focal or microscopic hemorrhage in a neurinoma is common, but tumor origin from the hypoglossal nerve and extensive symptomatic intratumoral hemorrhage are both rare. A 59-year-old male presented with severe neck pain, nausea and vomiting of 1-day duration, accompanied by right hypoglossal nerve palsy. Neuroimaging disclosed a tumor located in the right cerebellomedullary fissure and containing a hematoma. The right hypoglossal canal was slightly dilated. The intracranial tumor was resected via a suboccipital approach. Histological examination demonstrated spindle-shaped tumor cells with nuclear palisading and also relative hypervascularity with hyaline degeneration of the vessels. Extensive hemorrhage was present, as was necrosis. Thickening and hyalinization of arterial walls, a common occurrence in neurinomas, may have contributed to symptomatic intratumoral hemorrhage.

Publication types

  • Case Reports

MeSH terms

  • Cranial Nerve Neoplasms / complications
  • Cranial Nerve Neoplasms / diagnostic imaging*
  • Diagnosis, Differential
  • Humans
  • Hypoglossal Nerve / diagnostic imaging*
  • Hypoglossal Nerve / pathology
  • Hypoglossal Nerve / physiopathology
  • Hypoglossal Nerve Diseases / complications
  • Hypoglossal Nerve Diseases / diagnostic imaging*
  • Intracranial Hemorrhages / diagnostic imaging*
  • Intracranial Hemorrhages / etiology
  • Male
  • Middle Aged
  • Neurilemmoma / complications
  • Neurilemmoma / diagnostic imaging*
  • Tomography, X-Ray Computed