Towards an e-biology of ageing: integrating theory and data

Nat Rev Mol Cell Biol. 2003 Mar;4(3):243-9. doi: 10.1038/nrm1051.

Abstract

Ageing is a highly complex process; it involves interactions between numerous biochemical and cellular mechanisms that affect many tissues in an organism. Although work on the biology of ageing is now advancing quickly, this inherent complexity means that information remains highly fragmented. We describe how a new web-based modelling initiative is seeking to integrate data and hypotheses from diverse biological sources.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aging*
  • Animals
  • Cellular Senescence
  • Computer Simulation
  • Humans
  • Internet
  • Models, Biological*
  • Software
  • Time Factors