Microbial transformation of xanthohumol

Phytochemistry. 2003 Mar;62(5):673-7. doi: 10.1016/s0031-9422(02)00615-5.

Abstract

Microbial transformation of xanthohumol using the culture broth of Pichia membranifaciens afforded three metabolites, (E)-2"-(2"'-hydroxyisopropyl)-dihydrofurano[2",3":4',3']-2', 4-dihydroxy-6'-methoxychalcone, (2S)-2"-(2"'-hydroxyisopropyl)-dihydrofurano[2",3":7,8]-4'-hydroxy-5-methoxyflavanone and (E)-2"-(2"'-hydroxyisopropyl)-dihydrofurano[2",3":2',3']-4'-hydroxy-5-methoxychalcone.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biotransformation
  • Cyclization
  • Epoxy Compounds / chemistry
  • Fermentation
  • Flavonoids
  • Pichia / metabolism*
  • Propiophenones / chemistry
  • Propiophenones / metabolism*
  • Spectrum Analysis
  • Stereoisomerism

Substances

  • Epoxy Compounds
  • Flavonoids
  • Propiophenones
  • xanthohumol