Antibacterial activity and endotoxin-binding capacity of Actisorb Silver 220

J Hosp Infect. 2003 Mar;53(3):211-4. doi: 10.1053/jhin.2002.1369.

Abstract

Actisorb Silver 220 wound dressing demonstrated a high in vitro endotoxin-binding capacity combined with a marked bactericidal activity without releasing Pseudomonas aeruginosa endotoxins into the environment, and so may be beneficial in the treatment of infected wounds, particularly colonization by Gram-negative bacteria.

MeSH terms

  • Anti-Infective Agents, Local / pharmacology
  • Anti-Infective Agents, Local / therapeutic use*
  • Bandages / standards*
  • Charcoal
  • Endotoxins
  • Escherichia coli
  • Gram-Negative Bacterial Infections / microbiology
  • Gram-Negative Bacterial Infections / therapy
  • Humans
  • Materials Testing
  • Pseudomonas aeruginosa
  • Silver Sulfadiazine / pharmacology
  • Silver Sulfadiazine / therapeutic use*
  • Time Factors
  • Wound Infection / microbiology
  • Wound Infection / therapy*

Substances

  • Anti-Infective Agents, Local
  • Endotoxins
  • Charcoal
  • Silver Sulfadiazine