Abstract
Fifty-seven Shiga toxin-producing Escherichia coli (STEC) strains isolated from pigs with edema disease (ED) from 1997 to 2001 in Japan were examined for antimicrobial susceptibilities. The susceptibilities were compared with those of E. coli ATCC 23546 isolated from pig with ED in the 1950's. Consequently, the isolated STECs showed high susceptibility to peptides and bicozamycin in a way similar to the reference strain. On the other hand, the STECs showed low susceptibility to beta-lactams, tetracyclines, novobiocin, fosfomycin, trimethoprim, and old quinolones. It became clear that the susceptibilities of the isolated STECs had diminished in regard to antimicrobials.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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4-Quinolones
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Animals
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Anti-Bacterial Agents / pharmacology
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Anti-Infective Agents / pharmacology
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Bridged Bicyclo Compounds, Heterocyclic / pharmacology
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Edema Disease of Swine / drug therapy
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Edema Disease of Swine / microbiology*
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Escherichia coli / drug effects*
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Escherichia coli / isolation & purification
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Escherichia coli / metabolism
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Escherichia coli Infections / drug therapy
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Escherichia coli Infections / microbiology
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Escherichia coli Infections / veterinary*
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Fosfomycin / pharmacology
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Japan
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Lactams
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Microbial Sensitivity Tests / veterinary
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Novobiocin / pharmacology
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Peptides
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Swine
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Tetracyclines / pharmacology
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Trimethoprim / pharmacology
Substances
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4-Quinolones
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Anti-Bacterial Agents
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Anti-Infective Agents
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Bridged Bicyclo Compounds, Heterocyclic
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Lactams
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Peptides
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Tetracyclines
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Novobiocin
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Fosfomycin
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Trimethoprim
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bicozamycin