Evaluation of selective and non-selective enrichment PCR procedures for Salmonella detection

Lett Appl Microbiol. 2003;36(4):217-21. doi: 10.1046/j.1472-765x.2003.01294.x.

Abstract

Aims: To compare PCR combined with enrichment media with the standard microbiological techniques (SMT) and to determine the most sensitive method for the detection of Salmonella and the identification of Salm. typhimurium (ST), Salm. enteritidis (SE), Salm. gallinarum (SG) and Salm. pullorum (SP).

Methods and results: We analysed 87 samples from poultry using PCR and SMT, PCR being performed from non-selective (NS) and Rappaport-Vassiliadis (RV) media. PCR-NS was less sensitive than PCR-RV and SMT for the detection and identification of Salmonella. PCR-RV detected more positive samples of Salmonella sp. than SMT but both these methods showed similar sensitivity regarding the identification of Salmonella serovars.

Conclusions: PCR-RV was more sensitive and decreased the time necessary to detect and identify Salmonella.

Significance and impact of the study: PCR-RV is a powerful tool for the rapid and accurate detection and identification of Salmonella and can be implemented in diagnostic and food analysis laboratories.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacteriological Techniques* / statistics & numerical data
  • Base Sequence
  • DNA Primers / genetics
  • DNA, Bacterial / genetics
  • DNA, Bacterial / isolation & purification
  • Food Microbiology*
  • Humans
  • Polymerase Chain Reaction / methods*
  • Polymerase Chain Reaction / statistics & numerical data
  • Poultry / microbiology*
  • Salmonella / genetics*
  • Salmonella / isolation & purification*
  • Salmonella Food Poisoning / diagnosis
  • Salmonella Food Poisoning / microbiology
  • Salmonella Infections, Animal / diagnosis
  • Salmonella Infections, Animal / microbiology
  • Salmonella enteritidis / genetics
  • Salmonella enteritidis / isolation & purification
  • Salmonella typhimurium / genetics
  • Salmonella typhimurium / isolation & purification
  • Sensitivity and Specificity

Substances

  • DNA Primers
  • DNA, Bacterial