Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo

Adv Exp Med Biol. 2003:524:303-12. doi: 10.1007/0-306-47920-6_36.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Dipeptidyl Peptidase 4 / metabolism
  • Glucagon / metabolism*
  • Glucagon / pharmacology
  • Glucagon-Like Peptide 1
  • Glucagon-Like Peptides
  • Humans
  • Insulin / metabolism
  • Insulin Secretion
  • Kinetics
  • Mice
  • Molecular Sequence Data
  • Neprilysin / metabolism*
  • Peptide Fragments / chemistry
  • Peptide Fragments / metabolism*
  • Peptide Fragments / pharmacology
  • Protease Inhibitors / pharmacology
  • Protein Precursors / metabolism*
  • Protein Precursors / pharmacology

Substances

  • Insulin
  • Peptide Fragments
  • Protease Inhibitors
  • Protein Precursors
  • glucagon-like peptide 1 (7-36)amide
  • Glucagon-Like Peptides
  • Glucagon-Like Peptide 1
  • Glucagon
  • Dipeptidyl Peptidase 4
  • Neprilysin