Germline TP53 mutations in breast cancer families with multiple primary cancers: is TP53 a modifier of BRCA1?

J Med Genet. 2003 Apr;40(4):e34. doi: 10.1136/jmg.40.4.e34.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • BRCA1 Protein / genetics*
  • Breast Neoplasms / genetics*
  • DNA Mutational Analysis
  • DNA, Neoplasm / chemistry
  • DNA, Neoplasm / genetics
  • Family Health
  • Female
  • Gene Frequency
  • Germ-Line Mutation*
  • Humans
  • Male
  • Middle Aged
  • Mutation
  • Neoplasms, Multiple Primary / genetics*
  • Pedigree
  • Polymorphism, Genetic
  • Suppression, Genetic
  • Tumor Suppressor Protein p53 / genetics*

Substances

  • BRCA1 Protein
  • DNA, Neoplasm
  • Tumor Suppressor Protein p53