Is the measurement of thymidylate synthase to determine suitability for treatment with 5-fluoropyrimidines ready for prime time?

Clin Cancer Res. 2003 Apr;9(4):1235-9.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Blotting, Western
  • Colorectal Neoplasms / diagnosis
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / mortality
  • Disease Progression
  • Hepatic Artery / metabolism
  • Humans
  • Neoplasms / metabolism*
  • Pyrimidines / pharmacology*
  • Thymidylate Synthase / biosynthesis*

Substances

  • Pyrimidines
  • 5-fluoropyrimidine
  • Thymidylate Synthase