Effects of dextroamphetamine on psychomotor skills

Clin Pharmacol Ther. 1976 Jun;19(6):777-81. doi: 10.1002/cpt1976196777.

Abstract

Twelve healthy male volunteers were given 0, 5, 10, 15 mg/70 kg dextroamphetamine orally in a randomized double-blind fashion. Blood pressure increased linearly with dose while heart rate was unchanged. Although selected individual tests of stance stability and motor function improved in a dose-related fashion, a generalized improvement in performance was not found. Delayed Auditory Feedback (DAF) failed to show improvement in mental performance after dextroamphetamine.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Acoustic Stimulation
  • Adult
  • Blood Pressure / drug effects
  • Dextroamphetamine / pharmacology*
  • Feedback
  • Heart Rate / drug effects
  • Humans
  • Male
  • Motor Skills / drug effects*
  • Placebos
  • Postural Balance / drug effects

Substances

  • Placebos
  • Dextroamphetamine