Abstract
Patients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought. As compared with nonconverters (n = 10), converters (n = 7) had lower fluorodeoxyglucose uptake in the right temporoparietal cortex (p = 0.02, corrected for cluster size), without individual overlap. Awaiting replication in an independent sample, these findings suggest that among patients with MCI, fluorodeoxyglucose PET may accurately identify rapid converters.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alzheimer Disease / diagnostic imaging*
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Alzheimer Disease / epidemiology
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Brain / diagnostic imaging
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Disease Progression
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Female
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Fluorodeoxyglucose F18
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Gyrus Cinguli / diagnostic imaging
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Humans
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Male
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Memory Disorders / diagnostic imaging
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Middle Aged
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Neuropsychological Tests
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Parietal Lobe / diagnostic imaging
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Prospective Studies
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Radiopharmaceuticals
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Risk Factors
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Single-Blind Method
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Temporal Lobe / diagnostic imaging
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Tomography, Emission-Computed*
Substances
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Radiopharmaceuticals
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Fluorodeoxyglucose F18