Disseminated cytomegalovirus disease as a cause of prolonged fever in a bullous pemphigoid patient under systemic steroid therapy

J Dermatol. 2003 Apr;30(4):332-6. doi: 10.1111/j.1346-8138.2003.tb00396.x.

Abstract

We present the first reported case of disseminated cytomegalovirus (CMV) in association with prednisone therapy in bullous pemphigoid (BP). A 66-year-old black male patient was admitted to our hospital presenting cutaneous pruritic lesions represented by tense blisters, with serous content on the arms, abdomen and legs. Laboratory findings confirmed the diagnosis of BP. After two weeks of prednisone therapy, the patient developed prolonged fever, which was caused by CMV disseminated disease, with prompt clinical recovery after ganciclovir administration.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Biopsy, Needle
  • Cytomegalovirus Infections / complications*
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / drug therapy
  • Fever / complications*
  • Fever / diagnosis
  • Follow-Up Studies
  • Ganciclovir / administration & dosage
  • Humans
  • Immunocompromised Host
  • Immunohistochemistry
  • Male
  • Opportunistic Infections / complications*
  • Opportunistic Infections / diagnosis
  • Pemphigoid, Bullous / complications*
  • Pemphigoid, Bullous / drug therapy
  • Pemphigoid, Bullous / immunology
  • Prednisone / administration & dosage*
  • Prednisone / adverse effects
  • Risk Assessment
  • Treatment Outcome

Substances

  • Ganciclovir
  • Prednisone