High prevalence of PER-1 extended-spectrum beta-lactamase-producing Acinetobacter spp. in Korea

Antimicrob Agents Chemother. 2003 May;47(5):1749-51. doi: 10.1128/AAC.47.5.1749-1751.2003.

Abstract

PER-1, an extended-spectrum beta-lactamase, has been reported only in Europe. We detected PER-1 in 53 of 97 acinetobacters in Korea, mainly in the sputum of intensive care unit patients. Pulsed-field gel electrophoresis analysis suggested that clonal spread had occurred. Only PCR reliably detected PER-1 producers. PER-1 producers may also exist in other Asian countries.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acinetobacter / drug effects
  • Acinetobacter / enzymology*
  • Acinetobacter / genetics
  • Drug Resistance, Bacterial
  • Electrophoresis, Gel, Pulsed-Field
  • Korea
  • Pseudomonas aeruginosa / enzymology
  • beta-Lactamases / analysis*
  • beta-Lactamases / biosynthesis

Substances

  • beta-lactamase PER-1
  • beta-Lactamases