[Interventional radiological treatment of non-colorectal liver metastases]

Vestn Rentgenol Radiol. 1999 Sep-Oct:(5):22-7.
[Article in Russian]

Abstract

Transcatheter treatment was performed in 81 patients with unresectable non-colorectal liver metastases. Effectiveness increased in the following order: hepatic artery infusion--arterial chemoembolization--combined, arterial and portal vein oily chemoembolization. The mean survival rates for these methods were 8.2 +/- 5.3, vs 11.7 +/- 12.9 vs 13.6 +/- 6.8 mo, and 1-year survival rates 29% vs 46% vs 65%, respectively. Chemoembolization with doxorubicin-in-oil and gelatin sponge was the most effective technique. Interventional radiological procedures were effective in neuroendocrine liver metastases. The mean survival, 1- and 3-year survival rates were as high as 34 mo, 100% and 80%, respectively, for hepatic metastases from resected malignant carcinoid tumors. Also good results were achieved after chemoembolization of metastatic ovarian carcinoma and arterial infusion for gastric carcinoma metastatic to the liver. Transcatheter treatment was ineffective in liver metastases from pancreatic carcinoma, gallbladder cancer, and unknown (and non-resected) tumors. The initial results of the use of interventional radiological procedures in non-colorectal liver metastases are promising, so following clinical trails are needed.

MeSH terms

  • Adult
  • Aged
  • Angiography
  • Arterial Occlusive Diseases / diagnostic imaging
  • Arterial Occlusive Diseases / therapy*
  • Chemoembolization, Therapeutic
  • Colorectal Neoplasms / pathology*
  • Colorectal Neoplasms / radiotherapy*
  • Female
  • Hepatic Artery / diagnostic imaging
  • Humans
  • Liver Neoplasms / blood supply
  • Liver Neoplasms / secondary*
  • Liver Neoplasms / therapy*
  • Male
  • Middle Aged
  • Neoplasms, Second Primary
  • Ovarian Neoplasms / pathology*
  • Ovarian Neoplasms / radiotherapy*
  • Stomach Neoplasms / pathology*
  • Stomach Neoplasms / radiotherapy*