Vancomycin-associated linear IgA bullous dermatosis mimicking toxic epidermal necrolysis

J Am Acad Dermatol. 2003 May;48(5 Suppl):S56-7. doi: 10.1067/mjd.2003.116.

Abstract

Vancomycin is the most frequent trigger of drug-induced linear IgA bullous dermatosis. We describe a fulminant case of linear IgA bullous dermatosis in a 74-year-old man who experienced skin sloughing of 90% of his body surface after receiving vancomycin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / adverse effects*
  • Anti-Bacterial Agents / therapeutic use
  • Diagnosis, Differential
  • Humans
  • Immunoglobulin A / analysis
  • Male
  • Skin Diseases, Vesiculobullous / chemically induced*
  • Skin Diseases, Vesiculobullous / diagnosis
  • Staphylococcal Infections / drug therapy
  • Stevens-Johnson Syndrome / diagnosis*
  • Vancomycin / adverse effects*
  • Vancomycin / therapeutic use

Substances

  • Anti-Bacterial Agents
  • Immunoglobulin A
  • Vancomycin