Use of intravenous abciximab as adjunctive therapy for carotid angioplasty and stent placement

Int J Cardiovasc Intervent. 2003;5(2):61-6. doi: 10.1080/14628840310003235.

Abstract

The benefit of intravenous abciximab as an adjunctive to percutaneous coronary intervention has been demonstrated in large-scale randomized studies. The role of intravenous abciximab is being defined in carotid angioplasty and stent placement as the procedure is gaining popularity for the treatment of high-grade carotid stenosis in patients considered high-risk for carotid endarterectomy. This paper summarizes the pathophysiological basis and the available data for the use of abciximab as an adjunct to carotid artery stenting.

Publication types

  • Review

MeSH terms

  • Abciximab
  • Angioplasty, Balloon, Coronary / methods*
  • Antibodies, Monoclonal / administration & dosage*
  • Carotid Artery, Internal / surgery
  • Carotid Stenosis / drug therapy
  • Carotid Stenosis / surgery
  • Combined Modality Therapy
  • Humans
  • Immunoglobulin Fab Fragments / administration & dosage*
  • Infusions, Intravenous
  • Platelet Aggregation Inhibitors / administration & dosage*
  • Randomized Controlled Trials as Topic
  • Stents*

Substances

  • Antibodies, Monoclonal
  • Immunoglobulin Fab Fragments
  • Platelet Aggregation Inhibitors
  • Abciximab