Oncologic and functional results of near-total laryngectomy

Otolaryngol Head Neck Surg. 2003 May;128(5):700-5. doi: 10.1016/S0194-59980300095-0.

Abstract

Objective: To report the oncologic and functional outcome of patients undergoing near-total laryngectomy.

Study design and setting: A retrospective analysis was carried out from 1991 through 1998.

Results: Eighty-seven patients underwent near-total laryngectomy. The Kaplan-Meier overall survival, cause-specific survival, and relapse-free survival estimates at 5 years were 48.2%, 75.8%, and 72.4%, respectively. Univariate analysis revealed prognosis significance for location, stage, and pathologic cervical lymph node status. Five percent of the patients developed local recurrence, 16% recurrence in cervical lymph nodes, and 10% distant metastasis. Pharyngocutaneous fistula was the most frequent complication (48%). Seventy-seven percent of cases achieved voice preservation. Symptomatic aspiration was noted in 12.3% of cases.

Conclusion: Near-total laryngectomy can be a successful surgical procedure for selected patients; it does not replace total laryngectomy but reduces its indications. Voice preservation can be achieved in most cases.

Significance: Near-total laryngectomy enhances the speech rehabilitation options for the laryngectomy patient by adding a physiologic, nonprosthetic tissue technique.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Laryngeal Neoplasms / pathology
  • Laryngeal Neoplasms / surgery*
  • Laryngectomy / adverse effects
  • Laryngectomy / methods*
  • Male
  • Neoplasm Staging
  • Pharyngeal Neoplasms / pathology
  • Pharyngeal Neoplasms / surgery*
  • Prognosis
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome
  • Voice Disorders / etiology
  • Voice Disorders / prevention & control