Abstract
Shigellae are Gram-negative bacilli that cause bacillary dysentery in humans. This review summarizes current knowledge of Shigella pathogenesis and pathogenicity factors, invasion of epithelial cells, intracellular motility and cell-to-cell spreading, as well as components of the host cell involved in innate immune responses.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Dysentery, Bacillary / immunology*
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Dysentery, Bacillary / microbiology
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Epithelial Cells / microbiology*
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HeLa Cells
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Humans
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Immunity, Innate*
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Inflammation
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Intestinal Mucosa / microbiology*
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Shigella / immunology
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Shigella / pathogenicity*
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Virulence