Abstract
The sequence of the S gene of a field canine coronavirus (CCoV), strain Elmo/02, revealed low nucleotide (61%) and amino acid (54%) identity to reference CCoV strains. The highest correlation (77% nt and 81.7% aa) was found with feline coronavirus type I. A PCR assay for the S gene of strain Elmo/02 detected analogous CCoVs of different geographic origin, all which exhibited at least 92-96% nucleotide identity to each other and to strain Elmo/02. The evident genetic divergence between the reference CCoV strains and the newly identified Elmo/02-like CCoVs strongly suggests that a novel genotype of CCoV is widespread in the dog population.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Amino Acid Sequence
-
Animals
-
Cats
-
Coronavirus Infections / veterinary*
-
Coronavirus Infections / virology
-
Coronavirus, Canine / classification
-
Coronavirus, Canine / genetics*
-
Coronavirus, Feline / genetics
-
Diarrhea / veterinary*
-
Diarrhea / virology
-
Dog Diseases / virology*
-
Dogs
-
Feces
-
Genetic Variation*
-
Genotype
-
Italy
-
Membrane Glycoproteins / chemistry
-
Membrane Glycoproteins / genetics*
-
Molecular Sequence Data
-
Spike Glycoprotein, Coronavirus
-
Viral Envelope Proteins / chemistry
-
Viral Envelope Proteins / genetics*
Substances
-
Membrane Glycoproteins
-
Spike Glycoprotein, Coronavirus
-
Viral Envelope Proteins