The ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates

R P Limberger; L Ferreira; T Castilhos; A M Aleixo; R Z Petersen; J C Germani; J A Zuanazzi; A G Fett-Neto; A T Henriques

doi:10.1007/s00253-003-1270-2

The ability of Bipolaris sorokiniana to modify geraniol and (-)-alpha-bisabolol as exogenous substrates

Appl Microbiol Biotechnol. 2003 Jun;61(5-6):552-5. doi: 10.1007/s00253-003-1270-2. Epub 2003 Mar 25.

Authors

R P Limberger¹, L Ferreira, T Castilhos, A M Aleixo, R Z Petersen, J C Germani, J A Zuanazzi, A G Fett-Neto, A T Henriques

Affiliation

¹ Programa de Pós-Graduação em Ciências Farmacêuticas, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto Alegre, Rio Grande do Sul, Brazil.

PMID: 12764572
DOI: 10.1007/s00253-003-1270-2

Abstract

The biocatalytic potential of Bipolaris sorokiniana was investigated in its ability to modify the monoterpene geraniol and the sesquiterpene alpha-bisabolol as exogenous substrates, using phosphate buffer as reaction medium. The cultures showed a promising oxidative profile, with conversion of geraniol to 6-methyl-5-hepten-2-one (74.9% yield) in a 5-day incubation and alpha-bisabolol to bisabolol oxide B (84.2% yield), in a 7-day incubation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acyclic Monoterpenes
Ascomycota / metabolism*
Bioreactors
Biotechnology
Biotransformation
Culture Media
Monocyclic Sesquiterpenes
Sesquiterpenes / chemistry
Sesquiterpenes / metabolism*
Terpenes / chemistry
Terpenes / metabolism*

Substances

Acyclic Monoterpenes
Culture Media
Monocyclic Sesquiterpenes
Sesquiterpenes
Terpenes
bisabolol
geraniol