Evaluation of sodium T1 relaxation times in human heart

J Magn Reson Imaging. 2003 Jun;17(6):726-9. doi: 10.1002/jmri.10310.

Abstract

Purpose: To evaluate the sodium longitudinal relaxation (T(1)) characteristics for myocardium and blood in humans.

Materials and methods: Eleven healthy volunteers were examined by using a (23)Na heart surface coil at a 1.5 T clinical scanner equipped with a broadband spectroscopy option. (23)Na MR measurements were performed by using a three-dimensional spoiled gradient echo sequence (in-plane resolution, 3.5 mm x 7 mm; slice thickness, 24 mm; TE, 3.1 msec; bandwidth, 65 Hz/pixel; TR, 21 to 150 msec).

Results: Longitudinal T(1) relaxation time components were 31.6+/-7.0 msec and 31.1+/-7.5 msec for myocardium and blood, respectively.

Conclusion: (23)Na T(1) relaxation times of myocardium and blood can be determined in humans. The results are in agreement with values obtained from animal studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood
  • Echocardiography, Three-Dimensional
  • Female
  • Heart / anatomy & histology*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Myocardium / metabolism*
  • Reference Values
  • Sodium / metabolism*
  • Sodium Isotopes
  • Time Factors

Substances

  • Sodium Isotopes
  • Sodium