Abstract
The authors prospectively studied 98 patients with medication overuse headache. The 1-year relapse rate was 38% but was lower for patients with migraine compared with tension-type headache (22% vs 73%, p < or = 0.002) and combination of migraine and tension-type headache (22% vs 77%, p < or = 0.0001). The rate was also lower for patients overusing triptans than ergots (19% vs 20%, NS) and analgesics (19% vs 58%, p < or = 0.001). The long-term success of withdrawal depends on the type of primary headache and the type of overused medication.
MeSH terms
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Adult
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Aged
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Analgesics / adverse effects*
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Ergot Alkaloids / adverse effects*
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Female
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Germany / epidemiology
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Headache Disorders / chemically induced
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Headache Disorders / epidemiology*
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Humans
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Male
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Middle Aged
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Migraine Disorders / drug therapy
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Migraine Disorders / epidemiology
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Prospective Studies
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Recurrence
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Self Medication
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Serotonin Receptor Agonists / adverse effects*
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Surveys and Questionnaires
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Tension-Type Headache / drug therapy
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Tension-Type Headache / epidemiology
Substances
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Analgesics
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Ergot Alkaloids
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Serotonin Receptor Agonists