[Neurophysiology of parkinsonian syndromes]

Rev Neurol (Paris). 2003 May;159(5 Pt 2):3S62-74.
[Article in French]

Abstract

Neurophysiological investigations may contribute to establish the diagnosis of different parkinsonian syndromes such as multiple system atrophy, progressive supranuclear palsy and corticobasal degeneration, which are often suspected in case of atypical parkinsonian syndrome. They provide a means of objective analysis of certain symptoms (myoclonus for example) and identify the pathophysiological processes underlying these parkinsonian syndromes. This article reviews especially the following electrophysiological tests: autonomic nervous system analysis (sympathetic sudomotor skin response, R-R interval variation, electromyography of the external anal sphincter), surface electromyography and movement recording to investigate myoclonus, somatosensory and motor evoked potentials, brainstem reflexes (mainly the blink reflex), startle reaction, monosynaptic and long latency reflexes and finally the premotor potentials (contingent negative variation, Bereitschaftspotential) and movement-related desynchronization).

Publication types

  • English Abstract
  • Review

MeSH terms

  • Anal Canal / innervation
  • Anal Canal / physiopathology
  • Autonomic Nervous System Diseases / diagnosis
  • Autonomic Nervous System Diseases / physiopathology
  • Cognition Disorders / diagnosis*
  • Cognition Disorders / etiology*
  • Diagnosis, Differential
  • Electromyography
  • Evoked Potentials, Somatosensory / physiology
  • H-Reflex / physiology
  • Heart Rate / physiology
  • Humans
  • Magnetics
  • Median Nerve / physiopathology
  • Multiple System Atrophy / diagnosis
  • Multiple System Atrophy / physiopathology
  • Myoclonus / diagnosis
  • Neuropsychological Tests
  • Parietal Lobe / physiopathology
  • Parkinsonian Disorders / complications*
  • Parkinsonian Disorders / physiopathology
  • Respiration Disorders / diagnosis
  • Supranuclear Palsy, Progressive / diagnosis
  • Supranuclear Palsy, Progressive / physiopathology
  • Time Factors