[Studies of bi-derectional modulation effect of kudzuvine root on immunol cells]

Zhongguo Zhong Yao Za Zhi. 2002 Sep;27(9):684-7.
[Article in Chinese]

Abstract

Objective: To evaluate bi-directional modulation effect of Chinese herbal medicine on immunol cells.

Method: Two different active portions were isolated from Kudzuvine Root(Radix puerariae), one being the ethanol extraction and another the water extraction. Different concentration of these two different portions was studied by using PMA stimulated lymphocyte or eosinophil initiated chemiluminescence system.

Result: Water extraction of Kudzuvine Root could enhance chemiluminescence concentration dependently whereas enthanol extraction of Kudzuvine Root inhibited the chemiluminescence significantly.

Conclusion: The bi-directional regulation effect of Chinese herbal medicine can be found in the same herb, because of its efficacy of different active compounds.

Publication types

  • Comparative Study
  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Separation
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology*
  • Eosinophils / drug effects*
  • Ethanol
  • Humans
  • Luminescent Measurements
  • Lymphocytes / drug effects*
  • Plant Roots / chemistry
  • Plants, Medicinal* / chemistry
  • Pueraria* / chemistry
  • Water

Substances

  • Drugs, Chinese Herbal
  • Water
  • Ethanol