Mechanism of action of purine analogues in chronic lymphocytic leukaemia

Br J Haematol. 2003 Jun;121(5):692-702. doi: 10.1046/j.1365-2141.2003.04336.x.
No abstract available

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / metabolism
  • Antineoplastic Agents / pharmacology*
  • Apoptosis
  • Caspases / metabolism
  • Cell Division
  • Cladribine / metabolism
  • Cladribine / pharmacology*
  • DNA Damage
  • Drug Resistance, Neoplasm
  • Drug Synergism
  • Humans
  • Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
  • Pentostatin / metabolism
  • Pentostatin / pharmacology*
  • Phosphorylation
  • Tumor Suppressor Protein p53 / metabolism
  • Vidarabine / analogs & derivatives*
  • Vidarabine / metabolism
  • Vidarabine / pharmacology*

Substances

  • Antineoplastic Agents
  • Tumor Suppressor Protein p53
  • Pentostatin
  • Cladribine
  • Caspases
  • Vidarabine
  • fludarabine