Arterial thrombosis induced by IVIg and its treatment with tPA

Neurology. 2003 Jun 10;60(11):1825-6. doi: 10.1212/01.wnl.0000068334.04500.08.

Abstract

IV immunoglobulin therapy can lead to vascular events through increased serum viscosity and possibly other mechanisms. The authors describe the successful use of tissue plasminogen activator in three of four patients who developed cerebral and peripheral arterial thrombosis after treatment with IV immunoglobulin.

Publication types

  • Case Reports

MeSH terms

  • Arteries
  • Female
  • Humans
  • Immunoglobulins, Intravenous / adverse effects*
  • Intracranial Thrombosis / drug therapy
  • Intracranial Thrombosis / etiology
  • Male
  • Middle Aged
  • Peripheral Vascular Diseases / drug therapy
  • Peripheral Vascular Diseases / etiology
  • Thrombosis / drug therapy*
  • Thrombosis / etiology*
  • Tissue Plasminogen Activator / therapeutic use*

Substances

  • Immunoglobulins, Intravenous
  • Tissue Plasminogen Activator