Modulation of methylation in the FMR1 promoter region after long term treatment with L-carnitine and acetyl-L-carnitine

J Med Genet. 2003 Jun;40(6):e76. doi: 10.1136/jmg.40.6.e76.
No abstract available

Publication types

  • Letter
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetylcarnitine / therapeutic use*
  • Carnitine / therapeutic use*
  • Cells, Cultured
  • DNA Methylation / drug effects*
  • Fragile X Mental Retardation Protein
  • Fragile X Syndrome / drug therapy
  • Fragile X Syndrome / genetics
  • Humans
  • Intellectual Disability / drug therapy
  • Intellectual Disability / genetics
  • Nerve Tissue Proteins / genetics*
  • Nerve Tissue Proteins / metabolism*
  • Nootropic Agents / therapeutic use
  • Promoter Regions, Genetic / drug effects*
  • RNA-Binding Proteins / genetics
  • RNA-Binding Proteins / metabolism

Substances

  • FMR1 protein, human
  • Nerve Tissue Proteins
  • Nootropic Agents
  • RNA-Binding Proteins
  • Fragile X Mental Retardation Protein
  • Acetylcarnitine
  • Carnitine