Background: Solitary fibrous tumor (SFT) is a rare, benign, and very uncommon lesion in the orbit. Because of its complex and variable clinical and histological appearance the SFT is often misdiagnosed.
Cases: Two new cases of orbital SFT are reported, one in a man and the other in a woman, both unilateral and in the superomedial orbit.
Observations: Clinical and tomographical evaluations were conducted and the lesions were excised. The histological evaluation showed the tumors were composed of spindle-shaped cells within collagen bundles and vascular channels. Immunohistochemical staining was positive for CD 34 and negative for S-100 protein.
Conclusion: Immunohistochemical study is an important adjuvant in determining the SFT diagnosis. Long-term follow-up is necessary because of the possibility of SFT recurrence after excision.