[Inhaled corticosteroids in idiopathic pulmonary hemosiderosis: 2 cases]

Tunis Med. 2003 Apr;81(4):283-7.
[Article in French]

Abstract

Idiopathic pulmonary hemosiderosis, a rare clinical entity, is characterized by bleeding into the alveoli and progressive pulmonary fibrosis. It is usually treated with systemic corticosteriod during acute bleeding episodes and with prolonged courses of oral corticosteroids and/or other immunosuppressant drugs for maintenance therapy. Because prolonged treatment with these agents is frequently associated with significant side effects, favorable response to inhaled corticosteroids would be ideal in this condition. The authors reports 2 cases of idiopathic pulmonary hemosiderosis diagnoses in the pediatric department of Sfax: a 20 month old boy and an 8 year old girl successfully treated with inhaled beclomethazone dipropionate using doses of 500_g/day and low dose oral prednisolone (0.5 mg/kg one day/2).

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Administration, Inhalation
  • Beclomethasone / administration & dosage*
  • Child
  • Female
  • Glucocorticoids / administration & dosage*
  • Hemosiderosis / diagnosis
  • Hemosiderosis / drug therapy*
  • Humans
  • Infant
  • Lung Diseases / diagnosis
  • Lung Diseases / drug therapy*
  • Male
  • Prednisolone / administration & dosage*
  • Treatment Outcome

Substances

  • Glucocorticoids
  • Prednisolone
  • Beclomethasone