Colchicine treatment in conception and pregnancy: two hundred thirty-one pregnancies in patients with familial Mediterranean fever

O Rabinovitch; D Zemer; E Kukia; E Sohar; S Mashiach

doi:10.1111/j.1600-0897.1992.tb00805.x

Colchicine treatment in conception and pregnancy: two hundred thirty-one pregnancies in patients with familial Mediterranean fever

Am J Reprod Immunol. 1992 Oct-Dec;28(3-4):245-6. doi: 10.1111/j.1600-0897.1992.tb00805.x.

Authors

O Rabinovitch¹, D Zemer, E Kukia, E Sohar, S Mashiach

Affiliation

¹ Department of Gynecology and Obstetrics, Sheba Medical Center, Tel-Aviv University Medical School, Israel.

PMID: 1285892
DOI: 10.1111/j.1600-0897.1992.tb00805.x

Abstract

The effect of maternal use of colchicine on fetuses is unknown. The children of 116 women with Familial Mediterranean Fever (225 completed pregnancies) were studied. There was no unusual frequency of fetal abnormality among women taking colchicine before or during pregnancy. Colchicine treatment does not apparently harm mother or child.

MeSH terms

Abnormalities, Drug-Induced / etiology*
Abortion, Spontaneous / epidemiology
Cesarean Section / statistics & numerical data
Colchicine / adverse effects
Colchicine / pharmacology
Colchicine / therapeutic use*
Familial Mediterranean Fever / drug therapy*
Female
Follow-Up Studies
Humans
Infant, Newborn
Pregnancy
Pregnancy Complications / drug therapy*
Pregnancy Outcome / epidemiology

Substances

Colchicine