Increased interleukin-6 activity in cardiac myxoma with mediastinal lymphadenopathy

Intern Med. 1992 Oct;31(10):1207-9. doi: 10.2169/internalmedicine.31.1207.

Abstract

We report a case of cardiac myxoma with mediastinal lymphadenopathy which seems to be a very rare feature. Laboratory examination revealed high level of interleukin-6 (IL-6) activity in serum. Interestingly, after removal of cardiac myxoma, mediastinal lymphadenopathy disappeared on the chest CT and the level of serum IL-6 was decreased. These findings suggest that IL-6 which was probably derived from myxoma, may have played an important role in the development of lymphadenopathy.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Heart Neoplasms / complications
  • Heart Neoplasms / metabolism*
  • Heart Neoplasms / surgery
  • Humans
  • Interleukin-6 / biosynthesis*
  • Lymph Nodes / pathology
  • Lymphatic Diseases / etiology*
  • Mediastinal Diseases / etiology*
  • Middle Aged
  • Myxoma / complications
  • Myxoma / metabolism*
  • Myxoma / surgery
  • Tomography, X-Ray Computed

Substances

  • Interleukin-6