Abstract
An unusual monoterpene glycoside named dissectol A ( 1) was isolated from the EtOH extract of Incarvillea dissectifoliola, and its structure was determined by 1D and 2D NMR data. The antimicrobial bioassays showed that dissectol A had modest inhibitory activity against Mycobacterium tuberculosis when compared to rifampicin in an agar diffusion assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antitubercular Agents / administration & dosage
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Antitubercular Agents / chemistry
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Antitubercular Agents / pharmacology*
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Antitubercular Agents / therapeutic use
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Dose-Response Relationship, Drug
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Glycosides / administration & dosage
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Glycosides / chemistry
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Glycosides / pharmacology*
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Glycosides / therapeutic use
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Humans
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Magnoliopsida*
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Microbial Sensitivity Tests
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Monoterpenes / administration & dosage
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Monoterpenes / chemistry
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Monoterpenes / pharmacology*
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Monoterpenes / therapeutic use
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Mycobacterium tuberculosis / drug effects*
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Phytotherapy*
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Plant Components, Aerial
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Plant Extracts / administration & dosage
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Plant Extracts / chemistry
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
Substances
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Antitubercular Agents
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Glycosides
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Monoterpenes
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Plant Extracts
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dissectol A