Abstract
A new triterpene compound ( 1), along with arjunolic acid, was isolated from an ethanol extract of the whole plant of Leandra chaetodon. Based on spectroscopic analysis, the structure of 1 was determined as 2alpha,6alpha- dihydroxybetulinic acid. Arjunolic acid showed inhibitory activity against Cryptococcus neoformans. (IC50 = 20 micrograms/mL).
Publication types
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Antifungal Agents / administration & dosage
-
Antifungal Agents / pharmacology*
-
Antifungal Agents / therapeutic use
-
Cryptococcus neoformans / drug effects*
-
Humans
-
Microbial Sensitivity Tests
-
Myrtaceae*
-
Phytotherapy*
-
Plant Extracts / administration & dosage
-
Plant Extracts / pharmacology*
-
Plant Extracts / therapeutic use
-
Triterpenes / administration & dosage
-
Triterpenes / pharmacology*
-
Triterpenes / therapeutic use
Substances
-
Antifungal Agents
-
Plant Extracts
-
Triterpenes