High frequency of p53 dysfunction and low level of VH mutation in chronic lymphocytic leukemia patients using the VH3-21 gene segment

Blood. 2003 Aug 1;102(3):1145-6. doi: 10.1182/blood-2003-04-1289.
No abstract available

Publication types

  • Comment
  • Letter

MeSH terms

  • Humans
  • Immunoglobulin Heavy Chains / genetics*
  • Leukemia, Lymphocytic, Chronic, B-Cell / genetics
  • Leukemia, Lymphocytic, Chronic, B-Cell / immunology
  • Leukemia, Lymphocytic, Chronic, B-Cell / mortality*
  • Models, Biological
  • Molecular Diagnostic Techniques / methods
  • Prognosis
  • Somatic Hypermutation, Immunoglobulin
  • Tumor Suppressor Protein p53 / deficiency*
  • Tumor Suppressor Protein p53 / genetics

Substances

  • Immunoglobulin Heavy Chains
  • Tumor Suppressor Protein p53