Abstract
Objective:
To verify the mechanism of the hepatitis B viral clearance using clinical data.
Methods:
Viral level and HBV marker in serum were analyzed in 12 patients with acute hepatitis B.
Results:
The clearance of hepatitis B virus occurred before the patients were hospitalized in 66.7% of patients. The viral level and the A value of HBsAg;HBeAg declined gradually during hospitalization.
Conclusions:
In most of patients with acute hepatitis B in the study, the virus was cleared without destruction of infected cells.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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DNA, Viral / blood*
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Female
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Hepatitis B / virology*
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Hepatitis B Antibodies / blood
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Hepatitis B Core Antigens / blood
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Hepatitis B Surface Antigens / blood
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Hepatitis B e Antigens / blood
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Hepatitis B virus / genetics
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Hepatitis B virus / immunology
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Hepatitis B virus / isolation & purification*
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Humans
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Male
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Middle Aged
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Prognosis
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Retrospective Studies
Substances
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DNA, Viral
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Hepatitis B Antibodies
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Hepatitis B Core Antigens
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Hepatitis B Surface Antigens
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Hepatitis B e Antigens