Syntheses of second generation, 14-membered ring beta-turn mimics

Chem Commun (Camb). 2003 Jul 21:(14):1674-5. doi: 10.1039/b304454h.

Abstract

Efficient solid phase syntheses of the constrained beta-turn peptidomimetics 1-3 were devised, and the conformational properties of three representative compounds in DMSO were determined.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Biomimetics / methods*
  • Molecular Structure
  • Peptides, Cyclic / chemical synthesis*

Substances

  • Peptides, Cyclic