Impact of platinum complexes on dihydropyrimidine dehydrogenase activity in 5-fluorouracil-treated patients

Ann Oncol. 2003 Aug;14(8):1329-30. doi: 10.1093/annonc/mdg351.
No abstract available

Publication types

  • Comparative Study
  • Letter

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
  • Cisplatin / administration & dosage*
  • Cisplatin / adverse effects
  • Colorectal Neoplasms / drug therapy*
  • Colorectal Neoplasms / pathology
  • Dihydrouracil Dehydrogenase (NADP)
  • Drug Interactions
  • Fluorouracil / administration & dosage*
  • Fluorouracil / adverse effects
  • Head and Neck Neoplasms / drug therapy*
  • Head and Neck Neoplasms / pathology
  • Humans
  • Middle Aged
  • Neoplasm Staging
  • Oxidoreductases / drug effects
  • Oxidoreductases / metabolism*
  • Prognosis
  • Prospective Studies
  • Sampling Studies
  • Treatment Outcome

Substances

  • Oxidoreductases
  • Dihydrouracil Dehydrogenase (NADP)
  • Cisplatin
  • Fluorouracil