Frequency of stent thrombosis after acute coronary syndromes (from the SYMPHONY and 2nd SYMPHONY trials)

Am J Cardiol. 2003 Aug 1;92(3):330-3. doi: 10.1016/s0002-9149(03)00641-6.

Abstract

We studied stent thrombosis in 4,607 patients with acute coronary syndromes who received a coronary stent as part of routine care during 2 trials of aspirin versus sibrafiban for secondary prevention. In these patients, stent thrombosis occurred more often than in previous patients who underwent elective percutaneous coronary intervention. These patients and their outcomes may be more representative of patients with typical acute coronary syndromes undergoing stenting in clinical practice.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Aspirin / therapeutic use
  • Causality
  • Coronary Disease / therapy*
  • Coronary Thrombosis / epidemiology*
  • Female
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Myocardial Ischemia / drug therapy
  • Myocardial Ischemia / prevention & control
  • Oximes / therapeutic use
  • Piperidines / therapeutic use
  • Platelet Aggregation Inhibitors / therapeutic use
  • Postoperative Complications / epidemiology*
  • Stents / adverse effects*
  • Syndrome

Substances

  • Oximes
  • Piperidines
  • Platelet Aggregation Inhibitors
  • Aspirin
  • sibrafiban